Question 1

How are gluconeogenesis and glycolysis coordinated by nucleotides?

Accepted Answer

ATP inhibits glycolysis at PFK, while AD...

Question 2

The amount of glucose in the bloodstream and other body fluids is ________________.

Accepted Answer

20 g

Question 3

The ________________ cycle refers to the metabolic reactions by which glucose is converted into lactate in skeletal muscle, and then lactate is converted back into glucose in the liver.

Accepted Answer

Cori

Question 4

Explain how fructose 2,6-bisphosphate (F-2,6-BP) levels are regulated in the cell, and the relationship between F-2,6-BP levels and blood glucose levels.

Accepted Answer

The levels in the cell of F-2,6BP are re...

Question 5

The daily glucose requirement for a typical adult brain is ________________.

Accepted Answer

The answer of The daily glucose requirement for a typical...

Question 6

How many high-energy phosphate bonds are expended in gluconeogenesis?

Accepted Answer

A)   three
B)   six
C)   two
D)   four
E)   oneF) C) and D)
G) A) and B)

Question 7

Glucose 6-phosphatase takes place in which cellular location?

Accepted Answer

A)   the cytoplasm
B)   the endoplasmic reticulum
C)   the mitochondria
D)   the nucleus
E)   the plasma membraneF) A) and E)
G) B) and D)

Question 8

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-The conversion of glucose 6-phosphate to glucose takes place in the ____________.

Accepted Answer

A)  liver
B)  muscle
C)  one day
D)  endoplasmic reticulum
E)  gluconeogenesisF) phosphoenolpyruvate carboxykinaseG) PFK2H) CoriI) fructose 2,6-bisphosphateJ) magnesiumK) oxaloacetateL) biotinM) 2 hoursN) ATPO) L) and N)
P) F) and H)

Question 9

The bifunctional enzyme is also known as:

Accepted Answer

A)   phosphofructokinase I.
B)   phosphofructokinase II.
C)   fructose-1,6 phosphatase.
D)   protein kinase 2.
E)   phosphoenolpyruvate carboxykinase.F) A) and B)
G) A) and D)

Question 10

Phosphofructokinase (PFK)  is a highly regulated enzyme. Which of the following statements about PFK is correct?

Accepted Answer

A)   AMP and ADP both bind to and stabilize the inactive conformation of F6-P.
B)   ATP can overcome the inhibition by citrate.
C)   Citrate is an inhibitor of PFK.
D)   Acidic conditions from anaerobic metabolism activate PFK.
E)   None of the above.F) B) and E)
G) B) and C)

Question 11

The gluconeogenesis step responsible for reversing pyruvate kinase is ________________.

Accepted Answer

PEPCK

Question 12

ATP in the reaction catalyzed by PEPCK is used to fix ________________ to biotin.

Accepted Answer

The answer of ATP in the reaction catalyzed by PEPCK...

Question 13

High levels of ATP and citrate:

Accepted Answer

A)   indicate a high-energy-well-fed state.
B)   promote gluconeogenesis.
C)   inhibit glycolysis.
D)   All of the above.
E)   None of the above.F) A) and B)
G) A) and E)

Question 14

Hormonal activation of cyclic AMP levels:

Accepted Answer

A)   activates protein kinase A phosphorylation of FBPase2.
B)   phosphorylates PFK2 on a tyrosine residue.
C)   leads to the activation of PFK.
D)   activates the PKC phosphorylation of PFK2.
E)   increases the activation of gluconeogenesis.F) C) and D)
G) D) and E)

Question 15

The enzymes involved in shuttling carbons involved in gluconeogenesis from the mitochondria to the cytosol are called:

Accepted Answer

A)   malate dehydrogenase.
B)   citrate synthase.
C)   oxaloacetate transferase.
D)   oxaloacetate reductase.
E)   None of the above.F) A) and E)
G) C) and E)

Question 16

How are gluconeogenesis and glycolysis regulated reciprocally?

Accepted Answer

The enzymes involved in two substrate cy...

Question 17

Bumblebees are active when cold, while other insects are dormant. This is due to a high rate of ATP hydrolysis. What might help bring this about?

Accepted Answer

Futile cycles that involve ATP...

Question 18

Use the following to answer questions
Choose the correct answer from the list below. Not all of the answers will be used.
-____________: This essential nutrient is required for the carboxylation of pyruvate in humans.

Accepted Answer

A)  liver
B)  muscle
C)  one day
D)  endoplasmic reticulum
E)  gluconeogenesisF) phosphoenolpyruvate carboxykinaseG) PFK2H) CoriI) fructose 2,6-bisphosphateJ) magnesiumK) oxaloacetateL) biotinM) 2 hoursN) ATPO) C) and M)
P) A) and F)

Question 19

Lactate produced in muscle tissue is converted to ________________ by ________________.

Accepted Answer

A)   glucose / gluconeogenesis
B)   lactate / the Cori cycle
C)   glucose / the Cori cycle
D)   pyruvate / glycolysis
E)   ATP : the Krebs cycleF) C) and D)
G) B) and C)

Question 20

In general, the liver:

Accepted Answer

A)   does not utilize glucose under starvation/low-energy conditions.
B)   acts as a glucose buffer for the rest of the body.
C)   is a producer of glucose for the body under low-energy conditions.
D)   All of the above.
E)   None of the above.F) A) and E)
G) None of the above

Exam 17: Gluconeogenesis

How are gluconeogenesis and glycolysis coordinated by nucleotides?

Correct AnswerverifiedATP inhibits glycolysis at PFK, while AD...View AnswerShow Answer

The amount of glucose in the bloodstream and other body fluids is ________________.

Correct Answerverified20 g

The ________________ cycle refers to the metabolic reactions by which glucose is converted into lactate in skeletal muscle, and then lactate is converted back into glucose in the liver.

Correct AnswerverifiedCori

Explain how fructose 2,6-bisphosphate (F-2,6-BP) levels are regulated in the cell, and the relationship between F-2,6-BP levels and blood glucose levels.

Correct AnswerverifiedThe levels in the cell of F-2,6BP are re...View AnswerShow Answer

The daily glucose requirement for a typical adult brain is ________________.

Correct AnswerverifiedShow Answer

How many high-energy phosphate bonds are expended in gluconeogenesis?

Correct AnswerverifiedShow Answer

Glucose 6-phosphatase takes place in which cellular location?

Correct AnswerverifiedShow Answer

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -The conversion of glucose 6-phosphate to glucose takes place in the ____________.

Correct AnswerverifiedShow Answer

The bifunctional enzyme is also known as:

Correct AnswerverifiedShow Answer

Phosphofructokinase (PFK) is a highly regulated enzyme. Which of the following statements about PFK is correct?

Correct AnswerverifiedShow Answer

The gluconeogenesis step responsible for reversing pyruvate kinase is ________________.

Correct AnswerverifiedPEPCK

ATP in the reaction catalyzed by PEPCK is used to fix ________________ to biotin.

Correct AnswerverifiedShow Answer

High levels of ATP and citrate:

Correct AnswerverifiedShow Answer

Hormonal activation of cyclic AMP levels:

Correct AnswerverifiedShow Answer

The enzymes involved in shuttling carbons involved in gluconeogenesis from the mitochondria to the cytosol are called:

Correct AnswerverifiedShow Answer

How are gluconeogenesis and glycolysis regulated reciprocally?

Correct AnswerverifiedThe enzymes involved in two substrate cy...View AnswerShow Answer

Bumblebees are active when cold, while other insects are dormant. This is due to a high rate of ATP hydrolysis. What might help bring this about?

Correct AnswerverifiedFutile cycles that involve ATP...View AnswerShow Answer

Use the following to answer questions Choose the correct answer from the list below. Not all of the answers will be used. -____________: This essential nutrient is required for the carboxylation of pyruvate in humans.

Correct AnswerverifiedShow Answer

Lactate produced in muscle tissue is converted to ________________ by ________________.

Correct AnswerverifiedShow Answer

In general, the liver:

Correct AnswerverifiedShow Answer

Correct Answer
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ATP inhibits glycolysis at PFK, while AD...
View Answer

Correct Answer
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20 g

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Cori

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The levels in the cell of F-2,6BP are re...
View Answer

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PEPCK

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The enzymes involved in two substrate cy...
View Answer

Correct Answer
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Futile cycles that involve ATP...
View Answer

Correct Answer
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Lactate produced in muscle tissue is converted to by .

Correct Answer
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Correct Answer
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